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. 2017 May 11;7:1739. doi: 10.1038/s41598-017-01579-6

Table 4.

Statistics of meta-analyses for all included OPG SNPs.

SNP Major/minor allele No. of comparisons Sample size Heterogeneity Publication bias (P-value)a Model Meta-analyses
Patients Controls I b P-value Pooled OR 95% CI P-valueb
rs6993813 C/T 5 4725 37804 0.00% 0.994 0.653 Fixed 0.95 0.91–0.99 0.029
rs6469804 A/G 5 4725 37804 11.90% 0.338 0.161 Fixed 0.95 0.90–0.99 0.019
rs11995824 G/C 1 735 277 n.a. n.a. n.a. n.a. 1.01 0.82–1.24 0.920
rs3102735 C/T 4 769 979 63.30% 0.043 0.172 Random 0.98 0.68–1.42 0.921
rs3134070 G/A 1 532 262 n.a. n.a. n.a. n.a. 1.52 1.09–2.12 0.012
rs34353469 T/G 1 247 152 n.a. n.a. n.a. n.a. 0.89 0.65–1.23 0.484
rs2073617 T/C 3 1532 3091 0.00% 0.408 0.649 Fixed 1.06 0.92–1.22 0.394
rs2073618 C/G 5 3071 4815 0.00% 0.425 0.847 Fixed 0.89 0.83–0.97 0.004
rs3102734 G/A 1 1046 2303 n.a. n.a. n.a. n.a. 1.38 1.22–1.58 6.3E-05
rs3102733 T/C 1 247 152 n.a. n.a. n.a. n.a. 0.8 0.63–1.18 0.362
rs3134069 T/G 3 644 688 73.80% 0.022 0.648 Fixed 1.74 0.97–3.14 0.063
rs4355801 A/G 2 409 1019 0.00% 0.757 0.824 Fixed 0.98 0.83–1.16 0.849

aResults of Egger test; b P-value of significance was set at 0.004 by using the Bonferroni Correction. Supplementary materials included Tables S1S3, PRISMA checklist and PRISMA flow chart.