Table 1. A hypothetical example to demonstrate the danger of inflating statistical significance without removing redundancy.
The P-values are generated from the Chi-square test.
| Library | Original | 10x Amplified | ||||
|---|---|---|---|---|---|---|
| Count | Fold change | P-value | Count | Fold change | P-value | |
| A | 1 | 3.0 | 0.32 | 10 | 3.0 | 1.6e-3 |
| B | 3 | 30 | ||||