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. 2017 Feb 5;7(3):e2123. doi: 10.21769/BioProtoc.2123

Table 1. A hypothetical example to demonstrate the danger of inflating statistical significance without removing redundancy.

The P-values are generated from the Chi-square test.

Library Original 10x Amplified
Count Fold change P-value Count Fold change P-value
A 1 3.0 0.32 10 3.0 1.6e-3
B 3 30