. 2017 May 15;12(5):e0177215. doi: 10.1371/journal.pone.0177215

Table 4. Colorado NBS Population: Annual rate of change in FEV₁ percent predicted from childhood to adolescence by adolescent lung function quartile and Pa status before 6 years of age.

	Adolescent Lung Function Quartile
	Lowest quartile n = 43		2nd quartile n = 43		3rd quartile n = 43		Highest quartile n = 43
Mean (SD)	Pa negative n = 14	Pa positive n = 29	Pa negative n = 23	Pa positive n = 20	Pa negative n = 22	Pa positive n = 21	Pa negative n = 22	Pa positive n = 21
FEV₁ age 6–8	92.9 (±6.8)^*	79.7 (±13.2)	94.6 (±15.6)	89.5 (±7.1)^†	97.1 (±11.5)	93.9 (±11)^†^**	103.2 (±13)	107.4 (±12.4)^†^**
Annual rate of change in FEV₁% predicted	-2.6 (±0.9)	-2.8 (±2.5)	-1.2 (±1.9)	-0.9 (±1.1)	-0.4 (±1.6)^†	-0.1 (±1.4)^†	0.6 (±1.5)^†	-0.1 (±1.7)^†

* p<0.05 comparing Pa positive and negative groups within adolescent lung function quartile

† p<0.05 compared to lowest adolescent lung function quartile group with same Pa status

** p<0.05 compared to 2^nd adolescent lung function quartile group with same Pa status

Table 4. Colorado NBS Population: Annual rate of change in FEV1 percent predicted from childhood to adolescence by adolescent lung function quartile and Pa status before 6 years of age.