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. 2017 May 15;12(5):e0177744. doi: 10.1371/journal.pone.0177744

Fig 6. Effect of DCA treatment on PDK1 protein levels and PI3K/Akt pathway in RB.

Fig 6

(A) DCA treatment decreases protein levels of PDK1. (B) Treatment of RB cells with DAP results in reduced levels of PDK1 protein. (C) Treatment of RB cells with DCA leads to decreased PDK1 protein levels under hypoxia. (D) DCA alters the activity of PI3K/Akt pathway in RB cells.