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. 2017 May 15;12(5):e0177654. doi: 10.1371/journal.pone.0177654

Table 1. Baseline characteristics of study participants.

ACEI users ARB users
Characteristic (n = 34043) (n = 23772) P value
Age, year 60.5 ± 12.9 59.5 ± 12.8 <
0.001
Age group, year <
0.001
    <50 7912 (23.2) 5960 (25.1)
    50–65 12636 (37.1) 9310 (39.2)
    ≥65 13495 (39.6) 8502 (35.8)
Female sex 14350 (42.2) 10977 (46.2) <
0.001
Comorbidities
    Cardiovascular disease 11500 (33.8) 5285 (22.2) <
0.001
    Chronic kidney disease 4806 (14.1) 4110 (17.3) <
0.001
    Liver disease 7941 (23.3) 7243 (30.5) <
0.001
    Cancer 1558 (4.6) 1818 (7.6) <
0.001
Charlson comorbidity index <0.001
    0–3 8184 (24.0) 3623 (15.2)
    4–5 13478 (39.6) 9502 (40.0)
    ≥6 12381 (36.4) 10647 (44.8)
Geographic location <0.001
    Northern 12900 (37.9) 11289 (47.5)
    Middle 7733 (22.7) 4780 (20.1)
    Southern 11224 (33.0) 6289 (26.5)
    Eastern or other islands 2186 (6.4) 1414 (5.9)
Occupation <0.001
    White collar 14668 (43.1) 10939 (46.0)
    Blue collar 14923 (43.8) 10261 (43.2)
    Others 4452 (13.1) 2572 (10.8)
Income, NTD per month <0.001
    <15000 11129 (32.7) 7002 (29.5)
    15000–30000 18613 (54.7) 13389 (56.3)
    ≥30000 4301 (12.6) 3381 (14.2)
Year of index date <0.001
    1997–2003 15518 (45.6) 3849 (16.2)
    2004–2007 12033 (35.3) 10322 (43.4)
    2008–2010 6492 (19.1) 9601 (40.4)

Data are expressed as mean ± standard deviation for continuous variables and number (percentage) for categorical variables.

ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; NTD, New Taiwan Dollar.