Table 1. Relationship of BCL-9 expression and clinicopathological parameters in colorectal cancer patients (n = 284).
Variable | n | BCL-9 expression | p-value | ||
---|---|---|---|---|---|
− | + | ++ | |||
Gender | 0.894* | ||||
Male | 166 | 98 | 48 | 20 | |
Female | 118 | 68 | 37 | 13 | |
Age (yr) | 0.132* | ||||
< 65 | 161 | 101 | 42 | 18 | |
≥ 65 | 123 | 65 | 43 | 15 | |
Invasion depth | 0.000** | ||||
T1 | 3 | 3 | 0 | 0 | |
T2 | 82 | 66 | 13 | 3 | |
T3 | 195 | 97 | 71 | 27 | |
T4 | 4 | 0 | 1 | 3 | |
Lymph node metastasis | 0.000** | ||||
N0 | 205 | 132 | 55 | 18 | |
N1 | 71 | 34 | 24 | 13 | |
N2 | 8 | 0 | 6 | 2 | |
Distant metastasis | 0.191* | ||||
M0 | 282 | 166 | 83 | 33 | |
M1 | 2 | 0 | 2 | 0 | |
AJCC TNM stage | 0.000** | ||||
I | 72 | 62 | 7 | 3 | |
II | 133 | 70 | 47 | 16 | |
III | 77 | 34 | 29 | 14 | |
IV | 2 | 0 | 2 | 0 | |
Tumor pathological type | 0.527** | ||||
Adenocarcinoma | 258 | 148 | 80 | 30 | |
Mucinous adenocarcinoma | 15 | 10 | 3 | 2 | |
Papillary adenocarcinoma | 9 | 7 | 1 | 1 | |
Undifferentiated carcinoma | 1 | 0 | 1 | 0 | |
Signet-ring cell carcinoma | 1 | 0 | 0 | 1 |
* using Mann-Whitney U test;
** using Kruskal-Wallis test.