Figure 5. Compound K chemosensitizes CSCs via EMT.

A. Expression of CSC markers Bmi-1, Nanog, and Oct-4 or B. EMT markers Slug, Snail, E-cadherin, and N-cadherin were determined by RT-PCR or western blot after using cisplatin (CDDP; 50 μM) or paclitaxel (PTX; 100 nM) alone or in combination with compound K (CK) for 24 h. β-actin serves as an internal control. The signal intensity was determined by densitometry. Data are shown as mean ± SD. *, P < 0.05 vs control.