Table 1. TIDE algorithm predicted indels induced by each sgRNA.

Guide	Edition efficiency	TIDE Predicted Indels
Bcr-Abl sgRNA	85%	+1 bp (17.5%), −1 bp (9.1%), −2 bp (4.8%) −3 bp (3.4%), −4 bp (6%), −6 bp (1.8%), −8 bp (18.9%), −11 bp (10.2%), −18 bp (5.1%)
TK-ABL 1 sgRNA	54,6%	+1 bp (14.9%), −1 bp (8%) −2 bp (5.2%), −10 bp (17.6%)
TK-ABL 2 sgRNA	68,8%	+1 bp (30.8%), −1 bp (5.9%), −2 bp (4.8%), −4 bp (15.2%), −14 bp (5.1%)
Mock sgRNA	0%