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. 2017 Feb 16;8(16):26129–26141. doi: 10.18632/oncotarget.15387

Figure 1. ZNF521 is aberrantly overexpressed in MLL-rearranged AML.

Figure 1

(A) qRT-PCR for the expression of ZNF521 in 16 MLL-rearranged AML (MLL), 34 non-MLL-rearranged AML (Non-MLL) and 7 normal control (NC). The results are normalized to GAPDH and analyzed by 2−ΔCt method. NS, not significant, **P < 0.001, kruskal-Wallis test. (B) qRT-PCR analysis of ZNF521 expression in a representative panel of 12 human leukemic cell lines normalized to GAPDH and analyzed by 2−ΔCt method. Data are represented as mean ± SD of three independent experiments. y axis is linear. Inset, dot plots of mean ZNF521 mRNA levels in MLL-rearranged and non-MLL-rearranged cell lines from data presented in (B). *P < 0.05, Mann–Whitney U-test.