Figure 3. The relationship between CtBP2, p16^INK4A and patient survival.

(A) Based on mean CtBP2 percentages, patients were divided into high CtBP2 expressers (> 61.36%) and low CtBP2 expressers (≤ 61.36%). Patients in the high-expression CtBP2 group had significantly shorter overall survival. (B) Patients were also divided into two groups according to p16^INK4A expression both high expressers (> 37.14%) and low expressers (≤ 37.14%). Patients in the low-expression p16^INK4A group had significantly shorter overall survival. (C) Patients with CtBP2 (+)/p16^INK4A (−) phenotype (CtBP2 > 61.36% and p16^INK4A ≤ 37.14%) had the worst cumulative survival.