Table 1. Association of CtBP2 and p16^INK4A expression with clinicopathological parameters in 80 breast cancer specimens.

Parameters	Total	CtBP2 expression		P	p16INK4A expression		P
		Low ≤ 0.61	High > 0.61		Low ≤ 0.37	High > 0.37
Age (years)
≤ 50	31	12	19	0.135	14	17	0.187
> 50	49	11	38		16	33
Histological grade
Well	14	12	2	0.000*	0	14	0.004*
Mod	41	9	32		17	24
Poor	25	2	23		13	12
Metastasis
Positive	56	7	49	0.046*	28	28	0.047*
Negative	24	16	8		2	22
Tumor size(cm)
≤ 5	28	17	11	0.011*	17	11	0.043*
> 5	52	6	46		13	29
Histology
Ductal	65	17	48	0.117	23	42	0.316
others	15	6	9		7	8
ER
+	49	13	36	0.167	18	31	0.480
–	31	10	21		12	19
PR
+	47	12	35	0.183	20	27	0.511
–	33	11	22		10	23
HER2 status
+	26	11	15	0.103	14	12	0.157
–	54	12	42		16	38

Statistical analyses were performed by the Pearson χ² test.

*P < 0.05 is considered significant.