Table 3. Contribution of various potential prognostic factors to survival by Cox regression analysis in 80 breast carcinomas specimens.

	Hazard ratio	95% CI	P
Age (years)	1.732	0.875~3.430	0.115
Histological grade	2.489	1.505~4.118	0.000*
Metastasis	2.168	1.702~4.070	0.048*
Tumor size (cm)	2.815	1.376~3.766	0.044*
ER	0.476	0.213~0.987	0.314
PR	0.737	0.318~1.521	0.389
CtBP2	2.397	1.077~5.333	0.032*
p16INK4A	0.161	0.070~0.375	0.000*

Statistical analyses were performed by the log-rank test.

*P < 0.05 is considered significant.