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BALB/c nude mice were subcutaneously injected with control shRNA cells or RAB10 shRNA cells. (A) RAB10 knockdown significantly suppressed the formation and growth of xenografts. (B) Tumor volumes were measured on the indicated days. Knockdown of RAB10 decreased the volumes of xenografts significantly. (C) RAB10 knockdown reduced the weight of xenografts. Data were shown as means ± SD (n = 10), ***P < 0.001.
