Table 1. The viability of several human cell lines is unaffected by MpL.
Cell viability | ||||
---|---|---|---|---|
Cell line | Non-treated cells (viability - %) | Treated cells: 0.2 μM (relative viability - %) | Treated cells: 1 μM (relative viability - %) | Treated cells: 5 μM (relative viability - %) |
HeLa | 100.00 ± 1.85 | 105.60 ± 5.34 | 105.51 ± 0.65 | 107.26 ± 8.42 |
SH-SY5Y | 100.00 ± 7.41 | 110.10 ± 9.09 | 101.45 ± 5.13 | 104.44 ± 9.76 |
HepG2 | 100.00 ± 16.65 | 90.29 ± 5.85 | 122.42 ± 12.81 | 92.58 ± 24.54 |
MCF10A neoT | 100.00 ± 5.23 | 87.36 ± 10.74 | 116.28 ± 19.28 | 112.43 ± 22.06 |
U937 | 100.00 ± 2.27 | 97.78 ± 10.51 | 100.51 ± 2.80 | 113.78 ± 3.30 |
Differentiated U937 | 100.00 ± 5.74 | 111.97 ± 4.75 | 116.34 ± 4.26 | 119.78 ± 7.40 |
NK-92 | 100.00 ± 18.53 | 97.44 ± 6.73 | 68.11 ± 11.57 | 86.42 ± 9.37 |
Jurkat | 100.00 ± 8.98 | 92.93 ± 8.23 | 101.70 ± 6.52 | 104.73 ± 4.81 |
Cell viability of different cell lines as measured by the MTS assay shows no significant toxicity of lectin MpL at three different concentrations (0.2 μM, 1 μM and 5 μM).