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. 2017 Mar 2;8(16):26911–26917. doi: 10.18632/oncotarget.15850

Figure 2. No effect of miR-29a on tumour growth in a pancreatic cancer model.

Figure 2

Ela1-TAg+ mice, on the wildtype, miR-29a heterozygous and miR-29a knockout backgrounds, were monitored for pancreatic cancer growth by MRI every two weeks. (A) Total tumour volume was estimated at each time-point for wildtype, heterozygous and knockout female mice, and wildtype, heterozygous and knockout male mice (n = 24, 11, 9, 21, 14, 10). Each line indicates average tumour size across the group. (B) Individual square root transformed total predicted tumour volume curves for wildtype, heterozygous and knockout female and male mice (n = 24, 11, 9, 21, 14, 10). Time 0 corresponds to the first detected tumour time-point and each line indicates tumour size in a single mouse. (C) Violin plots showing the mean, standard deviation and kernel probability density of the % tumour increase every two weeks under each condition in female and male mice (n = 24, 11, 9, 21, 14, 10). The P values were calculated using two-sided Mann-Whitney U test.