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. 2017 Mar 6;8(16):26969–26978. doi: 10.18632/oncotarget.15926

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Copyright: © 2017 Chen et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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Direct manner: hTERT binds with p50 to increase CDX2 expression at the promoter level. Indirect manner: hTERT binds with p65 to improve the expression of KLF4, which activates the CDX2 promoter.