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. 2017 Feb 23;8(16):27137–27144. doi: 10.18632/oncotarget.15648

Table 2. Association between B7-H4 and clinicalpathological factors in NSCLC.

Variables No. of studies No. of patients Effects model OR (95%CI) p Heterogeneity
I2(%) Ph
Gender (male vs female) 8 1,128 Fixed 0.94(0.68-1.29) 0.699 0 0.65
Age (≥60 vs <60, years) 7 576 Fixed 0.92(0.65-1.29) 0.617 0 0.827
Histology (SCC vs ADC) 7 1,034 Random 2.35(0.77-2.36) 0.289 60.3 0.019
Lymph node metastasis (yes vs no) 6 527 Fixed 3.59(2.39-5.38) <0.001 26.5 0.235
TNM stage (III+IV vs I+II) 4 830 Random 2.36(1.2-4.67) 0.013 54.6 0.086
Differentiation (poor vs moderate/well) 4 347 Fixed 2.11(1.12-3.99) 0.021 0 0.583

Abbreviations: SCC: Squamous cell carcinoma; ADC: Adenocarcinoma