Table 5. Overall analysis of pathologic and oncological outcomes comparing LCA with PCA.
| Outcome of interest | No.of studies | No.of patients LCA/PCA |
OR (95%CI) | p-value | Study heterogeneity | |||
|---|---|---|---|---|---|---|---|---|
| Chi2 | df | I2 | p-value | |||||
| Pathologic | ||||||||
| Malignancy | 5 | 591/367 | 1.21[0.24,6.22] | 0.82 | 86.38 | 4 | 95% | <0.0001 |
| Benign | 5 | 591/367 | 0.77[0.16,3.74] | 0.74 | 83.84 | 4 | 95% | <0.0001 |
| Recurrence rate | 7 | 756/597 | 0.95[0.65,1.40] | 0.81 | 7.75 | 6 | 23% | 0.26 |
| 3-year DFS | 4 | 180/203 | 0.57[0.25,1.33] | 0.19 | 2.08 | 2 | 4% | 0.35 |
| 3-year OS | 5 | 252/234 | 0.87[0.48,1.55] | 0.63 | 3.23 | 4 | 0% | 0.52 |
| 5-year OS | 3 | 462/373 | 0.82[0.57,1.18] | 0.29 | 1.32 | 2 | 0% | 0.52 |
| 5-year RFS | 3 | 460/295 | 0.83[0.56,1.22] | 0.34 | 2.27 | 2 | 12% | 0.32 |
LCA=laparoscopic cryoablation; PCA=percutaneous cryoablation; DFS=disease-free survival; OS=overall survival; RFS=recurrence-free survival; OR = odds ratio; WMD = weighted mean difference; CI = confidence interval.