Skip to main content
. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Cancer. 2017 Mar 3;125(5):332–340. doi: 10.1002/cncy.21841

Table 6. Other CEC characteristics by diagnostic grouping.

Large nuclei Irregular nuclear boarders Anisonucleosis High N/C ratio Nuclear hyperchromasia
Malignant-Present n (%) 42 (46.7%) 52 (57.8%) 41 (45.6%) 23 (28.4%) 32 (35.6%)
Malignant-Absent n (%) 48 (53.3%) 38 (42.2%) 49 (54.4%) 58 (71.6%) 58 (64.4%)
Benign-Present n (%) 15 (60.0%) 18 (72.0%) 13 (52.0%) 6 (25.0%) 11 (44.0%)
Benign-Absent n (%) 10 (40.0%) 7 (28.0%) 12 (48.0%) 18 (75.0%) 14 (56.0%)
p= 0.27 0.25 0.17 0.80 0.49
Neoplastic-Present n (%) 52 (49.1%) 63 (59.4%) 52 (49.1%) 28 (28.9%) 39 (36.8%)
Neoplastic-Absent n (%) 54 (50.9%) 43 (40.6%) 54 (50.9%) 69 (71.1%) 67 (63.2%)
Non-neoplastic-Present n (%) 5 (55.6%) 7 (77.8%) 2 (22.2%) 1 (12.5%) 4 (44.4%)
Non-neoplastic-Absent n (%) 4 (44.4%) 2 (22.2%) 7 (77.8%) 7 (87.5%) 5 (55.6%)
p= 0.74 0.32 0.72 0.44 0.73
PDAC-Present n (%) 34 (47.2%) 42 (58.3%) 33 (45.8%) 20 (30.8%) 26 (36.1%)
PDAC-Absent n (%) 38 (52.8%) 30 (41.7%) 39 (54.2%) 45 (69.2%) 46 (63.9%)
NET-Present n (%) 3 (37.5%) 3 (37.5%) 3 (37.5%) 0 (0%) 2 (25.0%)
NET-Absent n (%) 5 (62.5%) 5 (62.5%) 5 (62.5%) 6 (100.0%) 6 (75.0%)
p= 0.72 0.46 0.72 0.17 0.71

CEC: Circulating epithelioid cells. PDAC: Pancreatic ductal adenocarcinoma. NET: Neuroendocrine tumor.