Table 4. Year 1 cytokine and behavior associations.

Associations between cell culture cytokine production after 48 hours of stimulation with TLR-4, TLR-3 agonist or in media and stereotyped behaviors measured around 1 year of age. Data presented as Spearman’s rank correlation coefficient and p-value. Only significant correlations are shown.

Postweaned Stereotyped Behaviors
	Cytokine	Spearman’s r	p-value
Media	IL-1β	0.735	0.001
	IL-6	0.601	0.002
	IL-10	0.570	0.014
	IL-12p40	0.590	0.003
	TNFα	0.584	0.006
	CCL2	0.547	0.006
	CCL4	0.603	0.005
	CXCL8	0.508	0.011
	G-CSF	0.656	0.003
	GM-CSF	0.500	0.035
TLR3	IL-1β	0.618	0.004
	IL-6	0.448	0.032
	IL-10	0.524	0.015
	IL-12p40	0.583	0.003
	CCL2	0.461	0.023
	CCL4	0.534	0.010
	CXCL8	0.524	0.009
	G-CSF	0.452	0.046
TLR4	IL-1β	0.524	0.010
	IL-6	0.539	0.010
	IL-10	0.471	0.031
	IL-12p40	0.465	0.025
	CCL3	0.438	0.032
	CXCL8	0.461	0.023
	G-CSF	0.642	0.001
	GM-CSF	0.441	0.046

CCL= Chemokine (C-C Motif) Ligand; CXCL=Chemokine (C-X-C Motif) Ligand; G-CSF=Granulocyte Colony Stimulating Factor; GM-CSF- Granulocyte Macrophage Colony Stimulating Factor; IL=interleukin; TLR= toll like receptor; TNF= tumor necrosis factor