Table 5. Year 4 cytokine and behavior associations.

Associations between cell culture cytokine production after 48 hours of stimulation with TLR-4 agonist, TLR-3 agonist or in media and self-directed stereotyped behaviors measured around 4 years of life. Data presented as Spearman’s rank correlation coefficient and p value. Only significant correlations are shown.

Sub-Adult Stereotyped Behaviors
Self Directed Stereotypies
Cytokine		Spearman r	p-value
TLR3	IL-4	0.445	0.034
	IL-5	0.645	0.016
	IL-12	0.499	0.015
	IL-17	0.482	0.023
	G-CSF	0.543	0.009
TLR4	IL-4	0.447	0.032
	IL-10	0.516	0.012
	IL-13	0.581	0.004

G-CSF=Granulocyte Colony Stimulating Factor; IL=interleukin; TLR= toll like receptor; TNF=tumor necrosis factor