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. 2017 May 15;7:1914. doi: 10.1038/s41598-017-02131-2

Table 1.

All the differentially expressed proteins identified by the iTRAQ experiments.

Accession Description Gene name -Leu/Ctrl (Set1|Set2) -Leu/Ctrl used for analysis
Proteins identified by the stringent criteria of unique peptide >1, P-value < 0.05, fold change >1.2 (or <0.833) in both the two sets of iTRAQ experiments
 Q86U79 Adenosine kinase ADK 1.969*|1.376* 1.673
 P57081 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 WDR4 0.830*|0.810* 0.820
 Q9UNS1 Protein timeless homolog TIMELESS 0.739*|0.773* 0.756
 P04264 Keratin, type II cytoskeletal 1 KRT1 0.776*|0.609* 0.693
 P13645 Keratin, type I cytoskeletal 10 KRT10 0.544*|0.567* 0.556
Proteins identified by the less stringent criteria of unique peptide >1, P-value < 0.05, fold change >2 (or <0.5) in any one set of the two iTRAQ experiments
 Q15493 Regucalcin RGN 12.059*|- 12.059
 Q9H2A2 Aldehyde dehydrogenase family 8 member A1 ALDH8A1 11.577*|- 11.577
 P00439 Phenylalanine-4-hydroxylase PAH 11.075*|- 11.075
 A5YKK6 CCR4-NOT transcription complex subunit 1 CNOT1 7.806*|- 7.806
 Q93088 Betaine–homocysteine S-methyltransferase 1 BHMT 7.652*|- 7.652
 P52758 Ribonuclease UK114 HRSP12 6.583*|- 6.583
 P05166 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 6.541*|- 6.541
 B3VL17 Beta globin (Fragment) HBB 6.408*|- 6.408
 Q3KPF3 Cytochrome P450, family 2, subfamily D, polypeptide 6 CYP2D6 6.326*|- 6.326
 P00326 Alcohol dehydrogenase 1 C ADH1C 6.317*|- 6.317
 Q9UI17 Dimethylglycine dehydrogenase, mitochondrial DMGDH 5.834*|- 5.834
 O75367 Core histone macro-H2A.1 H2AFY 5.740*|- 5.740
 P33121 Long-chain-fatty-acid–CoA ligase 1 ACSL1 5.621*|- 5.621
 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 5.152*|- 5.152
 P00480 Ornithine carbamoyltransferase, mitochondrial OTC 4.747*|- 4.747
 D4QEZ8 Short-chain acyl-CoA dehydrogenase ACADS 4.739*|- 4.739
 Q9Y365 PCTP-like protein STARD10 4.659*|- 4.659
 B2RBJ5 Alanine-glyoxylate aminotransferase 2 (AGXT2), nuclear gene encoding mitochondrial protein AGXT2 3.959*|- 3.959
 P83111 Serine beta-lactamase-like protein LACTB, mitochondrial LACTB 3.667*|- 3.667
 P00352 Retinal dehydrogenase 1 ALDH1A1 3.423*|- 3.423
 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic GPD1 3.393*|- 3.393
 P47989 Xanthine dehydrogenase/oxidase XDH 3.342*|- 3.342
 Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase ALDH1L2 3.299*|- 3.299
 Q16696 Cytochrome P450 2A13 CYP2A13 2.950*|- 2.950
 P26440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 2.722*|- 2.722
Q3LXA3 Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) DAK 2.606*|- 2.606
 P42357 Histidine ammonia-lyase HAL 2.559*|- 2.559
 O14975 Very long-chain acyl-CoA synthetase SLC27A2 2.343*|- 2.343
 P07858 Cathepsin B CTSB 2.212*|- 2.212
 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GNB2 2.207*|- 2.207
 P09417 Dihydropteridine reductase QDPR 2.140*|- 2.140
 Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial ETFDH 2.090*|- 2.090
 P09455 Retinol-binding protein 1 RBP1 2.087*|- 2.087
 P60953 Cell division control protein 42 homolog CDC42 2.032*|- 2.032
 P32189 Glycerol kinase GK 2.009*|- 2.009
 P61916 Epididymal secretory protein E1 NPC2 2.005*|- 2.005
 Q562E7 WD repeat-containing protein 81 WDR81 0.311*|- 0.311
 Q8N201 Integrator complex subunit 1 INTS1 0.292*|- 0.292

* P < 0.05.