Table 2.
CREB1 variant rs2253206 association with memory phenotypes for recessive, additive and dominant model of inheritance; controlling for IQ, gender, and age.
| Memory test | Assessed memory type | Recessive model |
Additive model |
Dominant model |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β | t | p | β | t | p | β | t | p | ||
| CAPM | Prospective memory | |||||||||
| IADL | –0.124 | –2.141 | 0.033 | –0.079 | –2.424 | 0.016 | –0.091 | –1.838 | 0.067 | |
| BADL | –0.039 | –0.840 | 0.401 | –0.033 | –1.260 | 0.208 | –0.046 | –1.190 | 0.235 | |
| Total | –0.052 | –1.161 | 0.246 | –0.041 | –1.624 | 0.105 | –0.056 | –1.466 | 0.143 | |
| MIST | Prospective memory | |||||||||
| Immediate | 0.059 | 0.371 | 0.711 | 0.141 | 1.576 | 0.116 | 0.280 | 2.068 | 0.039 | |
| Delay | 1.164 | 1.238 | 0.216 | 0.861 | 1.630 | 0.104 | 1.125 | 1.409 | 0.159 | |
| PRMQ | Prospective memory | –0.624 | –1.309 | 0.191 | –0.425 | –1.588 | 0.113 | –0.520 | 1.285 | 0.199 |
CREB1, cyclic adenosine monophosphate responsive element binding protein 1; CAPM, Comprehensive Assessment of Prospective Memory; IADL, instrumental activities of daily living; BADL, basic activities of daily living; MIST, Memory for Intentions Screening Test; PRMQ, Prospective and Retrospective Memory Questionnaire. Bolded values shows the p < 0.05.