Table 3.

Interactions between CREB1 genotype and APOE𝜀4 status significantly influence episodic memory controlling for baseline age, sex, and education.

SNP and grouping	Cognitive measure	Estimate/s, p-value, Cohen’s d SNP main effect	Estimate/s, p-value, Cohen’s d SNPx interval interaction	Estimate, p-value, Cohen’s d APOE𝜀4 main effect	Estimate, p-value, Cohen’s d APOE𝜀4x interval interaction	Estimate/s, p-value, Cohen’s d SNPx APOE𝜀4 interaction	Estimate/s, p-value, Cohen’s d interval SNPx APOE𝜀4 interaction
rs10932201 AA/GA vs GG	CVLT-immediate free recall	-0.145	-0.057	-2.486	0.010	3.564	-0.214
		0.83	0.438	0.388	0.251	0.029∗	0.201
		-0.02	-0.11	-0.27	0.02	0.38	-0.35
	CVLT-short-delay free recall	0.194	-0.017	-0.899	0.004	1.428	-0.070
		0.365	0.392	0.453	0.168	0.004∗∗	0.113
		0.07	-0.14	-0.34	0.03	0.54	-0.49
	CVLT-long-delay free recall	0.133	-0.023	-0.753	-0.014	1.094	-0.025
		0.522	0.198	0.389	0.204	0.022∗	0.555
		0.05	-0.14	-0.29	0.07	0.43	-0.21

The reference genotype group is underlined. Significant effects are shown in bold with ^∗ indicating significance at p = 0.05 and ^∗∗ at p = 0.01.