Table 2.

Basidiomycete laccase gene families.

Strain	Laccase number	Protein length (aa)	Identification	Major laccase(s)	Expression analysis	Detection	References
Auricularia auricula-judae	7	575–620	Transcriptome	Lcc3/5	Free-living and substrate mycelia and fruiting bodies	qRT-PCR	Fan et al., 2014
Cerrena sp. HYB07	8	516–542	Cloning	Lac2/7	Submerged fermentation	RT-PCR and LC-MS/MS	Yang et al., 2016a,b
Coprinopsis cinerea	17	516–567	Genome	Lcc1/5	Submerged fermentation	Zymograms and LC-MS/MS	Hoegger et al., 2004; Kilaru et al., 2006a; Rühl et al., 2013
Flammulina velutipes	11	502–607	Genome	Lac4	Mycelia and fruiting bodies	Transcriptome	Wang W. et al., 2015
Laccaria bicolor	9	504–540	Genome	LCC3/7	Mycelia, ectomycorrhizas and fruiting bodies	Custom whole-genome expression oligoarrays and qRT-PCR	Courty et al., 2009
Lentinula edodes	11	515–563	Genome	–	Mycelia, fruiting bodies	qRT-PCR	Sakamoto et al., 2015
Pleurotus ostreatus	11	516–541	Genome	Lacc2/10	Submerged fermentation, solid state fermentation, fruiting bodies	qRT-PCR	Castanera et al., 2012; Pezzella et al., 2013
Trametes hirsuta 072	5	519–523	cDNA library	LacA	Submerged fermentation	qRT-PCR	Vasina et al., 2015
Trametes sp. AH28-2	7	501–525a	Genome	LccA	Submerged fermentation	Native PAGE	Xiao et al., 2003, 2006; Zhang et al., 2015
Volvariella volvacea	11	508–562	Genome	Lcc3	Stipes	Digital gene expression (DGE) and qRT-PCR	Bao et al., 2013; Wu et al., 2013; Lu et al., 2015

^aThe length of LacA-C.