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. 2017 May 16;8:832. doi: 10.3389/fmicb.2017.00832

Table 3.

Laccase applications in biodegradation and bioremediation in 2016.

Compound Laccase Enzyme form Mediator References
PHENOLS
Chlorophenols, cresols, nitrophenols Trametes sanguineus laccase expressed in Trichoderma atroviride In culture Balcazar-Lopez et al., 2016
Technical nonylphenol Phoma sp. UHH 5-1-03 Free SA Hofmann and Schlosser, 2016
Oxybenzone, pentachlorophenol P. ostreatus Free ABTS, HBT, HPI, TEMPO, SA, VA, VAN Ashe et al., 2016
4-tert-butylphenol, 4-tert-octylphenol Myceliophthora thermophila laccase expressed in Aspergillus oryzae (Novozyme) Enzymatic membrane reactor SA Nguyen et al., 2016b
2,4-dichlorophenol Pycnoporus sanguineus CS43 Free Rodríguez-Delgado et al., 2016
DYESTUFFS
Bromophenol Blue, Congo Red, Coomassie Blue, Tripan Blue T. sanguineus laccase expressed in T. atroviride Free Balcazar-Lopez et al., 2016
Acid Black 172, Congo Red, Crystal Violet, Direct Fast Blue FBL, Indigo Blue, Naphthol Green B, Methylene Blue, Neutral Red, Reactive Brilliant Blue X-BR, Remazol Brilliant Blue Reactive (RBBR) T. pubescens Chitosan beads Zheng et al., 2016
Acid Orange 67, Basic Red 18, Basic Yellow 28, Direct Black 166, Direct Yellow 107, Disperse Yellow 79 Paraconiothyrium variabile Free HBT Forootanfar et al., 2016
Brilliant Blue G, Brilliant Blue R, Bromophenol Blue, Coomassie Blue R250, Crystal Violet, Malachite Green, Methylene Blue, Xylene Cyanol, RBBR P. sanguineus Free VA Iracheta-Cárdenas et al., 2016
RBBR T. versicolor (Sigma-Aldrich) Core-shell magnetic copper alginate beads HBT Le et al., 2016
RBBR Cerrena sp. HYB07 Cross-linked enzyme aggregates Yang et al., 2016c
Coomassie Blue R250 Cerrena sp. HYB07 Free ABTS, AS, HBT, SA, SYA Yang et al., 2016d,e
ENDOCRINE DISRUPTERS
Bisphenol A (BPA) Coriolopsis gallica, Bjerkandera adusta, T. versicolor Free HBT Daâssi et al., 2016
BPA T. sanguineus laccase expressed in T. atroviride In culture Balcazar-Lopez et al., 2016
BPA T. versicolor laccase expressed in S. cerevisiae Surface display ABTS Chen et al., 2016
BPA T. versicolor (Sigma-Aldrich) Cross-linked carbon nanotubes-based biocatalytic membranes Ji et al., 2016a
BPA M. thermophila laccase expressed in A. oryzae (Novozyme) On granular activated carbon, continuous flow packed-bed reactor Nguyen et al., 2016a
BPA, 17α-ethinylestradiol T. versicolor Polyamide 6/chitosan nanofibers Maryskova et al., 2016
BPA, 17α-ethinylestradiol Phoma sp. UHH 5-1-03 Free SA Hofmann and Schlosser, 2016
BPA, 17α-ethinylestradiol, 17α-estradiol, 17α-estradiol 17–acetate, estriol, estrone M. thermophila laccase expressed in A. oryzae (Novozyme) Enzymatic membrane reactor SA Nguyen et al., 2016b
POLYCYCLIC AROMATIC HYDROCARBONS (PAHs)
All 15 US EPA priority PAHs B. subtilis CotA expressed in E. coli Free ABTS Zeng et al., 2016
Naphthalene, phenanthrene T. versicolor (Sigma-Aldrich) Nonionic surfactant-modified clay Chang et al., 2016
Benzo[a]pyrene, phenanthrene T. sanguineus laccase expressed in T. atroviride Free Balcazar-Lopez et al., 2016
PESTICIDES
Atrazine P. ostreatus Free ABTS, HBT, HPI, TEMPO, SA, VA, VAN Ashe et al., 2016
Chlorpyrifos Bacterial WlacD expressed in Pseudomonas putida Surface display Liu et al., 2016
Atrazine, chlorothalonil, chlorpyrifos, isoproturon, pyrimethanil T. versicolor Free ABTS, AS, guaiacol, HBT, SA, VA, VAN Jin et al., 2016
Atrazine, isoproturon O. sativa laccases expressed in P. pastoris In culture Huang et al., 2016
Ametryn, atrazine, clofibric acid, fenoprop, pentachlorophenol, propoxur M. thermophila laccase expressed in A. oryzae (Novozyme) Enzymatic membrane reactor SA Nguyen et al., 2016b
MYCOTOXINS
Aflatoxin B1 and M1 P. pulmonarius Free ABTS, AS, SA Loi et al., 2016

All tested mediators are listed. ABTS, 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonate); AS, acetosyringone; HBT, 1-hydroxybenzotriazole; HPI, N-hydroxyphthalimide; TEMPO, 2,2,6,6-tetramethylpiperidinyloxyl; SA, syringaldehyde; SYA, syringic acid; VA, violuric acid; VAN, vanillin.