Table 1.
Characteristics of patients grouped by serum vitamin D concentration
| Characteristic | 25(OH)D < 20 ng/mL (n = 135) | 25(OH)D ≥ 20 ng/mL (n =29) | p value |
|---|---|---|---|
| Demographic | |||
| Age at transplantation, yr | 46.22 ± 12.26 | 48.21 ± 13.89 | 0.236 |
| Male sex (recipient) | 94 (69.6) | 22 (75.9) | 0.503 |
| Pre-transplant BMI, kg/m2 | 21.90 ± 3.20 | 21.35 ± 3.38 | 0.511 |
| Etiologies of ESRD | 0.043 | ||
| Diabetic nephropathy | 41 (30.4) | 5 (17.2) | |
| Hypertension | 5 (3.7) | 5 (17.2) | |
| Glomerulonephritis | 80 (59.3) | 17 (58.6) | |
| Other | 9 (6.7) | 2 (6.9) | |
| Renal replacement therapy before KT | 0.136 | ||
| HD | 76 (56.3) | 23 (79.3) | |
| PD | 20 (14.8) | 3 (10.3) | |
| HD + PD | 3 (2.2) | 0 | |
| Preemptive KT | 36 (26.7) | 3 (10.3) | |
| Transplant type | 0.006 | ||
| Living donor | 80 (59.3) | 9 (31.0) | |
| Deceased donor | 55 (40.7) | 20 (69.0) | |
| Donor characteristics | |||
| Donor age, yr | 44.83 ± 14.47 | 44.63 ± 16.19 | 0.523 |
| Cold ischemic time, min | 159.26 ± 141.98 | 211.21 ± 128.27 | 0.014 |
| Total HLA mismatch | 3.10 ± 1.64 | 3.24 ± 1.62 | 0.576 |
| HLA-DR mismatch | 1.07 ± 0.67 | 1.00 ± 0.76 | 0.652 |
| Laboratory results (pre-transplant) | |||
| 25(OH)D, ng/mL | 10.97 ± 4.69 | 27.34 ± 8.70 | < 0.001 |
| Hemoglobin, g/dL | 10.35 ± 1.68 | 11.64 ± 1.36 | < 0.001 |
| WBC, /μL | 6,966.51 ± 2,673.72 | 6,939.29 ± 2,451.27 | 0.843 |
| BUN, mg/dL | 57.39 ± 32.68 | 47.55 ± 19.80 | 0.288 |
| Creatinine, mg/dL | 8.97 ± 4.32 | 9.15 ± 3.14 | 0.505 |
| Sodium, mmol/L | 137.26 ± 4.13 | 138.20 ± 4.13 | 0.212 |
| Potassium, mmol/L | 4.70 ± 0.78 | 4.81 ± 0.68 | 0.529 |
| Blood sugar, mg/dL | 130.84 ± 84.93 | 108.54 ± 28.92 | 0.334 |
| Desensitization | 22 (16.3) | 6 (20.7) | 0.589 |
Values are presented as mean ± SD or number (%).
25(OH)D, 25-hydroxyvitamin D; BMI, body mass index; ESRD, end-stage renal disease; KT, kidney transplantation; HD, hemodialysis; PD, peritoneal dialysis; HLA, human leukocyte antigen; WBC, white blood cell; BUN, blood urea nitrogen.