TABLE 4.
Comparison of growth properties and virulence of wild and mouse-adapted H7 viruses
| Virusa | Subtype | HA titer | TCID50/mlb | EID50/mlb | MLD50/ml |
|---|---|---|---|---|---|
| A/Anhui/1/13 | H7N9 | 128 | 7.0 | 8.2 | 6.0 |
| A/EM/Korea/W109/06 | H7N7 | 128 | 7.3 | 8.3 | >8.3 |
| A/AB/Korea/W44/05 | H7N3 | 128 | 7.8 | 8.4 | >8.4 |
| A/EM/Korea/W478/14 | H7N7 | 128 | 6.1 | 8.2 | >8.2 |
| A/EM/Korea/W410/11 | H7N9 | 128 | 6.8 | 8.4 | >8.4 |
| Ma109/06 | H7N7 | 128 | 7.5 | 8.9 | 5.5 |
| Ma44/05 | H7N3 | 256 | 7.8 | 9.1 | 5.5 |
| Ma478/14 | H7N7 | 128 | 6.5 | 8.3 | 6.0 |
| Ma410/11 | H7N9 | 256 | 7.3 | 8.4 | 5.5 |
AB, aquatic bird; EM, environment; Ma, mouse adaptation.
TCID50 and EID50 values were measured in MDCK cells and 12-day-old embryonated chicken eggs, respectively.