FIG 3.

Expanded CD8^hCXCR5 and untransduced CD8 T-cell cultures have similar phenotypic profiles. Flow cytometry analysis for memory differentiation marker expression (CD95⁺/CD28⁺) and PD-1 and ICOS expression on CD8^hCXCR5 and untransduced CD8 T-cell cultures expanded ex vivo from animal 1 1 week before infusion and a fresh PBMC sample from a similar infected rhesus macaque outside the study group are presented. Samples are identified above each column with central memory and effector memory gates denoted by CM and EM labels, respectively.