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Maintenance of ICOS expression in CD8hCXCR5 T cells. Representative flow cytometry analysis plots for ICOS and PD-1 expression in CD3+ T cells isolated from spleen and lymph node samples from animal 4 are presented. Gating for endogenous CTV− CD4− (top) and CTV+ CD8hCXCR5 T cells (bottom) cells are denoted above each plot.
