Table 2.
Univariate and multivariate analyses of overall survival for 172 patients with nonmucinous appendiceal adenocarcinoma
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | (95% CI) | P value | HR | (95% CI) | P value | |
| Presence of signet ring cells | 1.59 | (1.06–2.39) | 0.03 | 0.97 | (0.60–1.56) | 0.90 |
| Poorly differentiated histology | 3.03 | (2.02–4.53) | <0.01 | 0.52 | (0.24–1.12) | 0.10 |
| Lymph node involvement (N1 vs. N0) | 2.37 | (1.38–4.06) | <0.01 | 2.20 | (1.23–3.92) | 0.01 |
| Lymph node metastasis (Nx vs. N0) | 4.63 | (2.86–7.49) | <0.01 | 3.12 | (1.52–6.44) | <0.01 |
| Advanced T stage (T4 vs. T1-T3) | 1.64 | (0.94–2.85) | 0.08 | 1.70 | (0.04–3.10) | 0.08 |
| Distant metastasis | 3.58 | (2.36–5.41) | <0.01 | 2.87 | (1.28–6.44) | 0.01 |
| Age > or = 50 yrs. vs. < 50 yrs. | 1.09 | (0.73–1.61) | 0.67 | |||
| Male vs. Female | 1.41 | (0.96–2.07) | 0.08 | |||
| Race: White vs. Non-White | 0.87 | (0.49–1.55) | 0.63 | |||
Abbreviations: HR hazard ratio, CI, confidence interval