Table 1.
Characteristics of 307 patients with primary thymoma and their association with recurrence
| Variable | Whole cohort (n = 307) | Patients with recurrence (n = 52)a | P |
|---|---|---|---|
| Age (years) | 0.314 | ||
| ≤60 | 244 (79.5) | 44 (18.0) | |
| >60 | 63 (20.5) | 8 (12.7) | |
| Sex | 0.942 | ||
| Female | 149 (48.5) | 25 (16.8) | |
| Male | 158 (51.5) | 27 (17.1) | |
| Tumor size (cm) | 0.950 | ||
| ≤6.5 | 170 (55.4) | 29 (17.1) | |
| >6.5 | 137 (44.6) | 23 (16.8) | |
| Myasthenia gravis | 0.749 | ||
| Yes | 58 (18.9) | 9 (15.5) | |
| No | 249 (81.1) | 43 (17.3) | |
| WHO histological classification | <0.001 | ||
| A | 19 (6.1) | 1 (5.3) | |
| AB | 99 (32.2) | 5 (5.1) | |
| B1 | 61 (19.9) | 7 (11.5) | |
| B2 | 83 (27.0) | 26 (31.3) | |
| B3 | 45 (14.7) | 13 (28.9) | |
| Masaoka stage | <0.001 | ||
| I | 74 (24.1) | 3 (4.1) | |
| II | 170 (55.4) | 17 (10.0) | |
| III | 52 (16.9) | 24 (46.2) | |
| IVa | 11 (3.6) | 8 (72.7) | |
| Surgical approach | 0.590 | ||
| Transsternal | 97 (31.6) | 14 (14.4) | |
| Transthoracic | 140 (45.6) | 27 (19.3) | |
| VATS | 70 (22.8) | 11 (15.7) | |
| Postoperative radiotherapy | 0.006 | ||
| Yes | 142 (46.3) | 15 (10.6) | |
| No | 165 (53.7) | 37 (22.4) |
All values are presented as number of patients followed by percentage in parentheses
WHO World Health Organization, VATS video-assisted thoracoscopic surgery
aThe percentages in this column was calculated according to the following formula: the number of patients with recurrence/the number of relevant patients in the whole cohort