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. 2017 May 16;8(3):e00646-17. doi: 10.1128/mBio.00646-17

FIG 3 .

FIG 3 

Glutathionylation of LcrV enhances bubonic plague pathogenesis. (A) Survival of cohorts of BALB/c mice (n = 20) infected via subcutaneous (s.c.) inoculation with 20 CFU of Y. pestis CO92 lcrV or Y. pestis TD1 lcrVC273A. WT versus lcrVC273A, P < 0.0001. (B) Survival of cohorts of Brown Norway rats (n = 15) infected via subcutaneous inoculation with 500 CFU of Y. pestis CO92 or TD1. WT versus lcrVC273A, P = 0.0194. Statistical analysis was performed using the Gehan-Breslow-Wilcoxon test. Data are representative of two independent experiments.