Table 2.
Correlation between MEG3 methylation probes and prognostic miRNAs
| Methylation probe | Distance from MEG3 TSS | Correlation with 14q32 prognostic miRNAs | Number of miRNAs | Overlap with CTCF binding site |
|---|---|---|---|---|
| cg1656 | 1326 | None | None | Near site (in promoter) |
| cg0928 | 775 | 0.466 (0.596 to 0.404) | 7 | In site (in promoter) |
| cg2583 | 156 | 0.459 (0.528 to 0.396) | 3 | Near site (in promoter) |
| cg05711 | −218 | −0.561 | 1 | Near site (within gene body) |
| cg1537 | −628 | −0.443 (−0.408 to −0.631) | 13 | Near site (within gene body) |
| cg1510 | −1264 | 0.546 (0.621 to 0.428) | 2 | Near site (within gene body) |
| cg0429 | −1968 | −0.283 (−0.554 to −0.552) | 10 | Not in site (within gene body) |
Locations of MEG3 promoter and gene body methylation probes with respect to MEG3 transcription start sites (TSSs), CTCF binding sites, and correlation with the 14q32 prognostic miRNAs associated with proliferation (p < 0.1)