Table 2.

Substrate scope for the syntheses of compounds 4 and 6.^a

Entry	Starting materials	GBB product 4	Yieldb (%)	Cyclized product 6	Yieldb (%)
1		4b	94	6b	72
2		4c	80	6c	75
3		4d	62	6d	61
4		4e	96	6e	63
5		4f	89	6f	78
6		4g	61	6g	80
7		4h	85	6h	56
8		4i	88	6i	58
9		4j	64	6j	78
10		4k	75	6k	87
11		4l	49	6l	79
12		4m	71	6m	48
13		4n	47	6n	55
14		4o	54	6o	62
15		4p	95	6p	63
16		4q	74	6q	58
17		4r	43	6r	67
18		4s	57	6s	59

^aGBB reaction conditions: 1 (0.5 mmol), 2 (0.5 mmol), 3 (0.6 mmol), MeOH (1 mL); PTSA (5%), room temperature, 12h; annulation conditions: substrate 4 (0.2 mmol), Au(JohnPhos)Cl (10 mol %), CH₃CN (2 mL) at reflux temperature for 24 h. ^bIsolated yields.