Left: Hemodynamics (heart rate, mean arterial pressure) in WT (n=14) and Kv.1.3−/− (n=15) mice under basal conditions, during hexamethonium, and during norepinephrine infusion (with hexamethonium). Right: Hemodynamics of WT mice following correolide administration (Corr80 [80 ng/kg, n=6] and Corr800 [800 ng/kg, n=8]) before and during norepinephrine.