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. 2016 Aug 18;18(17):4440–4443. doi: 10.1021/acs.orglett.6b02323

Table 3. Selectivity Based on Electronic Bias.

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a

General reaction conditions: 1.0 equiv of aryl chloride, 0.13 M dioxane/H2O (2:1), 2.3 equiv of R2(CH2)2Bpin, 1 mol % Pd2(dba)3, 6 mol % FcPPh2, 6.0 equiv of K3PO4, 18–20 h, 100 °C.

b

Isolated yield.

c

1.5 equiv of R2(CH2)2Bpin, 3.0 equiv of K3PO4.

d

Not detected by 1H NMR.

e

Exhaustively coupled product (6% yield) was detected by crude 1H NMR.

f

48 h.

g

Isolated after reaction with trifluoroacetic acid.

h

2 mol % Pd2(dba)3, 12 mol % FcPPh2.