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. 2017 Jan-Mar;15(1):1–3. doi: 10.1590/S1679-45082017AE3844

Chart 6. Measures for secondary prevention of adverse reactions to intravenous immunoglobulin.

Slower rate of infusion in patients with prior reaction
Pre-medication with analgesics and/or nonsteroidal anti-inflammatory drugs, H1 (and anti H2) antihistamines, and corticosteroids
Pre-hydration with 0.9% saline solution
Switch product or consider subcutaneous Ig in case of major reactions with no response to symptomatic drugs

Ig: immunoglobulin.