. 2017 Jan-Mar;15(1):105–111. doi: 10.1590/S1679-45082017RW3827

Table 3. Summary of pooled effects.

	Number of studies	Homozygous			Recessive			Number of studies	Dominant			Co-dominant

		OR (95%CI) p value	P_het	I²	OR (95%CI) p value	P_het	I²		OR (95%CI) p value	P_het	I²	OR (95%CI) p value	P_het	I²
Overall	9	5.55 (1.86-16.55) 0.002	0.03	52	3.23 (1.86-5.59) <0.0001	<0.0001	85	10	3.14 (1.91-5.17) <0.0001	<0.0001	83	3.14 (1.93-5.10) <0.0001	<0.0001	86
HWE only	8	9.45 (2.91-30.71) 0.0002	0.02	57	7.19 (2.61-19.82) <0.0001	0.09	43	9	2.99 (1.78-5.02) <0.0001	<0.0001	85	3.08 (1.84-5.14) <0.0001	<0.0001	88
Italian studies only	7	11.12 (2.44-50.71) 0.002	0.02	59	8.72 (2.27-33.53) 0.002	0.07	49	8	3.83 (2.28-6.45) <0.0001	<0.0001	76	3.86 (2.40-6.21) <0.0001	<0.0001	78
Brazil*	1	2.35 (0.39-14.34)	-	-	1.95 (0.32-11.83)	-	-	1	2.28 (1.35-3.85)	-	-	2.05 (1.28-3.29)	-	-
Poland*	1	1.84 (0.45–7.50)	-	-	1.83 (0.45-7.42)	-	-	1	1.08 (0.70-1.67)	-	-	1.11 (0.75-1.65)	-	-

* Odds ratio and 95% confidence interval are study-specific values.

OR: odds ratio; 95%CI: 95% confidence interval; P_het: p value for heterogeneity; I² are expressed in %.