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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Metab Eng. 2016 Oct 19;38:446–463. doi: 10.1016/j.ymben.2016.10.009

Table 3.

Specific productivity of pathways constructed from 3HP/4HB cycle

Pathway Growth mode Productivity (nmol product/min/mg) CO2 fixation rate (nmol C/min/mg) Compared to native cycle (%) Potential productivity (nmol product/min/mg)
Native cycle - 159 159 100 181a
Acetyl-CoA autotrophic 75 149 94 85b
Succinate autotrophic 23 90 57 26b
Succinate heterotrophic 107 215 135 61b
3HP heterotrophic 421 421 265 140b
a

Assuming a 5-h doubling time and 50% cell dry weight as protein

b

Assuming similar expression levels of pathway enzymes as in M. sedula