Table 1. UHRF1 gene expression values regarding the demographic and selected clinicopathological parameters in urinary bladder TCC versus control patient’s samples and differences between the urinary bladder TCC subgroups.
| Patients groups | Demographic and clinicopathological patient subgroups | Patients number n (%) | UHRF1 expression (mean±SE) | Difference vs. control group (p-value) | Difference between the two subgroups (p-value) | |
|---|---|---|---|---|---|---|
| TCC | Total | 70 (100) | 1.47±0.25 | 0.1826 | / | |
|
| ||||||
| Gender | Male | 61 (87.14) | 1.53±0.28 | 0.3090 | 0.4719 | |
| Female | 9 (12.86) | 1.02±0.34 | 0.0814 | |||
| Smoking history | No | 23 (32.86) | 1.56±0.48 | 0.2332 | 0.7546 | |
| Yes | 47 (67.14) | 1.42±0.29 | 0.2664 | |||
| Tumor number | Solitary | 41 (58.57) | 1.75±0.36 | 0.0348* | 0.0927 | |
| Multiple | 29 (41.43) | 1.06±0.30 | 0.9177 | |||
| Tumor size (cm) | ≤3 | 38 (54.29) | 1.09±0.25 | 0.4268 | 0.4330 | |
| >3 | 32 (45.71) | 1.91±0.45 | 0.1275 | |||
| Grades | Low | 41 (58.57) | 0.72±0.11 | 0.9060 | 0.0090** | |
| High | 29 (41.43) | 2.53±0.52 | 0.0057** | |||
| Stages | Non-muscle invasive | 53 (75.71) | 1.09±0.24 | 0.6222 | 0.0305* | |
| Muscle invasive | 17 (24.29) | 2.65±0.62 | 0.0087** | |||
| Outcome | Good | 44 (62.86) | 0.93±0.20 | 0.4654 | 0.1127 | |
| Poor | 26 (37.14) | 2.37±0.54 | 0.0410* | |||
|
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| Control | Total | 40 (100) | 0.58±0.03 | / | / | |
|
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| Gender | Male | 34 (85.00) | 1.58±0.03 | / | 0.6359 | |
| Female | 6 (15.00) | 1.60±0.05 | / | |||
*and**, p<0.05 and p<0.01, respectively, versus control; SE = standard error.