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. 2017 May 16;11:221. doi: 10.3389/fnhum.2017.00221

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Copyright © 2017 Wang, Dong, Guan, Wu, He, Zou, Chen, Shi, Liang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Group comparison of the insula-centered functional connectivity (FC). (A) Seed region in the right aINS with altered baseline activities in psychogenic erectile dysfunction (pED). (B) Cortical areas that show significant differences between the two groups (pED vs. normal controls (NCs)). Aberrant connectivity patterns were observed within the right aINS, and between the right aINS and the right dlPFC and the right temporoparietal junction (TPJ) respectively. Between group differences are assessed by means of two-sample t analysis (p < 0.05 AlphaSim corrected). Abbreviations: aINS, anterior insula, dlPFC, dorsolateral prefrontal cortex, TPJ, the temporoparietal junction.