Table 1.
Characteristics of patients.
| Patients (n) | Female (%) | Age (years) | FLCs in CSF | index | Lambda index | |
|---|---|---|---|---|---|---|
| Control group | ||||||
| Group 1: NPH | 41 | 11 (26.8) | 75.72 (40–87) | 0.16 (0.10–0.22) | 1.62 (0.99–2.27) | 1.28 (0.93–1.68) |
| Group 2: NIND | 15 | 10 (66.7) | 39.11 (15–71) | 0.12 (0.10–0.20) | 3.37 (1.95–7.05) | 1.35 (0.96–1.90) |
| Group 3: IND | 14 | 9 (64.3) | 44.77 (30–75) | 0.13 (0.04–0.20) | 2.86 (1.47–7.00) | 1.10 (0.81–2.71) |
| Total | 70 | 30 (42.9) | 61.69 (15–87) | 0.15 (0.10–0.20) | 1.96 (1.13–3.56) | 1.27 (0.93–1.69) |
| Case group | ||||||
| Group 4: CIS | 77 | 60 (77.9) | 35.26 (15–62) | 0.73 (0.13–3.2) | 35.61 (4.48–132.73) | 3.81 (1.49–16.95) |
| Group 5: RRMS | 29 | 17 (58.6) | 34.81 (17–57) | 1.45 (0.52–6.67) | 88 (33.96–295.13) | 5.43 (2.01–19.40) |
| Total of patients | 176 | 107 (60.8) | 45.70 (15–87) | |||
The patients were divided in five groups: the control group was classified in three subgroups: normal pressure hydrocephalus (NPH), other non-inflammatory neurologic disease (NIND) different from NPH and other inflammatory neurologic disease (IND) different from multiple sclerosis (MS); case group: Clinically isolated syndrome (CIS) and relapsing–remitting multiple sclerosis (RRMS). Data are shown as the mean and the range for age; kappa free light chains (FLCs) in cerebrospinal fluid (CSF), index and lambda index were found to be non-parametric after applying the Shapiro-Wilk test, so we calculated the median level and the interquartile range (IQR).