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Mean weighted genetic risk score in healthy controls, sporadic and multiplex MS patients.
| Controls n = 2028 | Sporadic MS n = 283 | Multiplex MS n = 169 | P value controls vs sporadic MS | P value controls vs multiplex MS | P value sporadic MS vs multiplex MS | |
|---|---|---|---|---|---|---|
| wGRS102 | 11.14 ± 0.67 | 11.48 ± 0.70 | 11.60 ± 0.65 | <0.0001 | <0.0001 | 0.08 |
| wGRS102+HLA | 11.44 ± 0.86 | 12.04 ± 0.88 | 12.39 ± 0.96 | <0.0001 | <0.0001 | <0.0001 |
wGRS: weighted genetic risk score.
Means and standard deviations are indicated for wGRS.
