Table 14:
Comparable Pharmacogenomic Panels to Support Psychotropic Medication Selection
| Company | Assurex | CNSdose | CRL Corp | Genele X | Genomind | MDL-Labs |
|---|---|---|---|---|---|---|
| Test | GeneSight | CNSDose | SureGene | You Script psychotropic plus | Genecept | Psychiatric pharmacogenetic |
| Websitea | https://genesight.com/ | https://www.cnsdose.com/ | http://www.crlcorp.com/services/personalized-medicine/tests/ | http://genelex.com/ | https://genomind.com/ | http://www.mdllabs.com/providers/tests/psychiatric-pharmacogenetic-test-panel |
| Number of genes | 8b | 3c | 19 | 12 | 19 | 4 |
| List of genes | ABC transportersc | |||||
| ADRA2A | ADRA2A | |||||
| ANK3 | ||||||
| BDNF | ||||||
| CACNA1C | ||||||
| COMT | COMT | COMT | ||||
| CYP1A2 | CYP1A2 | CYP1A2 | CYP1A2 | |||
| CYP2B6 | CYP2B6 | CYP2B6 | CYP2B6 | |||
| CYP2C19 | CYP2C19 | CYP2C19 | CYP2C19 | CYP2C19 | ||
| CYP2C9 | CYP2C9 | CYP2C9 | CYP2C9 | |||
| CYP2D6 | CYP2D6 | CYP2D6 | CYP2D6 | CYP2D6 | ||
| CYP3A4 | CYP3A4 | CYP3A4 | CYP3A4 | CYP3A | ||
| CYP3A5 | CYP3A5 | |||||
| CYP450c | DRD2 | |||||
| FOLH1 | ||||||
| GLP1R | GRIK4 | GRIK1 | ||||
| HLA-A | ||||||
| HTR2A | 5HTR2A | HTR2A | ||||
| 5HTR2C | HTR2C | 5HT2C | ||||
| MC4R | ||||||
| MTHFR | MTHFR | MTHFR | ||||
| OPRM1 | OPRM1 | |||||
| SLC6A4 | SLC6A4 | SLC6A4/5-HTT | SLC6A4 | |||
| SULT4A1 | ||||||
| UGT1A1 | ||||||
| VKORC1 |
a
All websites were accessed on May 2, 2016.
b
Included genes were based on the application received from Assurex for review.
c
Specific genes in these gene groups were not identified on the company website, or in the academic paper by Singh et al.38 We are aware of two other similar tests, but we were unable to locate specific details about these tests at the time of this review. These tests are psynome2 by psynomics and PsychINDx by curidium medica.