Table 2.
A Summary of Exposure to Hg From Hib-Containing Vaccine Administration Within the First 15 Months of Life for the Cases Diagnosed With a Studied Abnormal Connectivity Spectrum Disorder and Controls.
| Group Examined (ICD-9 Code) | 25 μg Hg (%; Reference Dose) | 50 μg Hg (%) | 75 μg Hg (%) | 100 μg Hg (%) | Odds Ratio per 25 μg Hg (95% CI; P Value) |
|---|---|---|---|---|---|
| ASD cases (299.xx) | 26 (6.5) | 28 (7) | 265 (66.1) | 82 (20.4) | 1.493 (1.359-1.627; <.001) |
| Controlsa | 2327 (15.8) | 1960 (13.4) | 8517 (58.1) | 1863 (12.7) | |
| Tic disorder cases (307.2x) | 14 (5.8) | 20 (8.3) | 162 (67.2) | 45 (18.7) | 1.428 (1.256-1.600; <.001) |
| Controlsb | 2371 (14.7) | 2014 (12.5) | 9639 (59.9) | 2074 (12.9) | |
| ADD/ADHD cases (314.xx) | 104 (10) | 82 (7.9) | 676 (64.9) | 179 (17.2) | 1.503 (1.425-1.582; <.001) |
| Controlsb | 2174 (21.7) | 1748 (17.5) | 4997 (50) | 1078 (10.8) |
Abbreviations: ADD/ADHD, attention deficit disorder/attention deficit hyperactivity disorder; ASD, autism spectrum disorder; CI, confidence interval; Hg, mercury; Hib, Haemophilus influenzae type b; ICD-9, International Classification of Disease, Ninth Revision.
aThese controls were followed to the mean age of initial diagnosis plus twice the standard deviation.
bThese controls were followed to the mean age of initial diagnosis plus 1 standard deviation.