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. 2017 Mar 15;8:2041731417698852. doi: 10.1177/2041731417698852

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — (a) First appearance of capillary sprouting was seen when colony-forming LOEC proliferated and surrounded EOEC (arrow). Formation of long tubular capillaries was found only in the presence of LOSMC in cultures cultivated with SGM-2. During cultivation, (b) these structures became more and more complex and (c) LOSMC participated in the tube formation. These cultures could be cultivated for about 4 weeks without signs of overgrowth. (d) In this time, capillaries grew up to a length of up to 4.5 cm.