Table 1. Baseline characteristics of the study population.
| Characteristic | Chloroquine (n = 104) | Artemether-lumefantrine (n = 100) | Chloroquine plus primaquine (n = 102) | Artemether-lumefantrine plus primaquine (n = 92) |
|---|---|---|---|---|
| Health centre, n (percent) | ||||
| Bishoftu | 79 (76.0%) | 73 (73.0%) | 79 (77.5%) | 76 (82.6%) |
| Batu | 25 (24.0%) | 27 (27.0%) | 23 (22.5%) | 16 (17.4%) |
| Male, n (percent) | 64 (61.5%) | 70 (70.0%) | 68 (66.7%) | 51 (55.4%) |
| Age (years), median (IQR) | 18 (IQR 10.5–19.0) | 18 (IQR 10.0–26.0) | 17 (IQR 9.0–25.0) | 18 (IQR 9.0–27.0) |
| Age, n (percent) | ||||
| ≤5 y | 7 (6.7%) | 12 (12.0%) | 10 (9.8%) | 8 (8.7%) |
| 5–15 y | 31 (29.8%) | 31 (31.0%) | 37 (36.3%) | 28 (30.4%) |
| >15 y | 66 (63.5%) | 57 (57.0%) | 55 (53.9%) | 56 (60.9%) |
| Weight (kg), median (IQR) | 50.0 (29.0–56.0) | 48.0 (24.5–56.5) | 46.0 (22.0–54.0) | 45.5 (22.0–57.0) |
| Temperature (°C), median (IQR) | 36.8 (36.1–38.4) | 37.3 (36.4–39.0) | 37.3 (36.2–38.8) | 37.0 (36.4–38.2) |
| Fever, n (percent) | 37 (35.6%) | 46 (46.0%) | 43 (42.1%) | 50 (54.3%) |
| History of fever, n (percent) | 100 (98.0%) | 98 (99.0%) | 100 (99.0%) | 90 (97.8%) |
| Haemoglobin (g/l), mean (SD) | 136 (±17) | 137 (±20) | 134 (±19) | 135 (±18) |
| Parasitaemia (μl−1), geometric mean (95% CI) | 6,378 (5,133.1–7,924.3) | 6,691 (5,464.7–8,193.0) | 5,598 (4,492.6–6,975.4) | 5,132 (4,036.8–6,523.6) |
| Gametocyte carriage, n (percent) | 42 (40.4%) | 47 (47.0%) | 39 (38.2%) | 43 (46.7%) |
| G6PD status, n (percent) | ||||
| Normal | 100 (97.1%) | 90 (93.8%) | 102 (100.0%) | 92 (100.0%) |
| Intermediate | 3 (2.9%) | 6 (6.3%) | 0 | 0 |
| Deficient | 0 | 0 | 0 | 0 |
| Bednet use and insecticide use, n (percent) | ||||
| Household ownership of a bednet | 33 (34.7%) | 42 (42.0%) | 36 (35.3%) | 37 (40.7%) |
| Patient slept under bednet on the night before enrolment | 14 (13.5%) | 17 (17.0%) | 22 (21.6%) | 22 (23.9%) |
| House was sprayed with insecticides | 23 (22.1%) | 22 (22.0%) | 19 (18.6%) | 18 (19.6%) |
IQR, interquartile range; SD, standard deviation.