Table 10. Adverse events associated with CART procedures.
Adverse events | Patients | Sessions | Time point (sessions) | Severity (sessions) | |||
---|---|---|---|---|---|---|---|
During ascites drainage | During reinfusion | After reinfusion | Severe | Not severe | |||
Shock | 1 (0.7%) | 1 (0.3%) | 1 | 0 | 0 | 1 | 0 |
Hypotension | 4 (2.7%) | 4 (1.1%) | 4 | 0 | 0 | 0 | 4 |
Chest pain | 1 (0.7%) | 1 (0.3%) | 1 | 0 | 0 | 0 | 1 |
Abdominal pain | 1 (0.7%) | 1 (0.3%) | 1 | 0 | 0 | 0 | 1 |
Dyspnea | 1 (0.7%) | 1 (0.3%) | 1 | 0 | 0 | 0 | 1 |
Hyperammonemia | 1 (0.7%) | 1 (0.3%) | 0 | 0 | 1 | 0 | 1 |
Total | 9 (6.2%) | 9 (2.5%) | 8 | 0 | 1 | 1 | 8 |
Most of the adverse events associated with CART procedures were not severe, except one case of hemorrhagic shock at ascites drainage.