Table 2. Association between the MC4R rs12970134 polymorphism and appetite.

Variables	Means±SD			β'a	Pa	β'b	Pb	Pc	Pd
	GG(n = 91)	AG(n = 56)	AA(n = 4)
FR	2.44±0.70	2.66±0.89	3.35±1.25	0.196	0.017	0.177	0.028	0.176	0.265
SR	2.37±0.50	2.28±0.57	1.78±0.27	-0.148	0.072	-0.153	0.064	-0.030*	-0.026*
EF	3.61±0.77	3.62±0.84	4.06±0.83	0.031	0.699	0.021	0.792	-0.885*	-0.760*

a: Standerdized β and P values of rs12970134 in children using Linear regression models adjusted for age and gender; b: In children adjusted for age, gender and BMI-sds; c: PBAT P values of rs12970134 in trios adjusted for age and gender. d: In trios adjusted for age, gender and BMI-sds.

* Negative P values were used in PBAT output for negative association.

P values < 0.05 are shown in bold.

MC4R: Melanocortin-4 receptor; FR: Food responsiveness; SR: Satiety responsiveness; EF: Enjoyment of food.